• About
About

About

Laura D’Ignazio, Ph.D. joined the Lieber Institute in January 2019 as a post-doctoral fellow in the Dr. Jennifer Erwin’s laboratory. She currently investigates disease-causal mechanisms to identify therapeutic targets for X-linked Dystonia Parkinsonism (XDP), an incurable and fatal neurodegenerative movement disorder caused by an inherited mobile element mutation. Laura earned her B.S. degree in Biotechnology and two M.S. degrees in Industrial Biotechnology and Molecular Biology from the University of Urbino “Carlo Bo” in Italy. In 2011, she moved to Baltimore for the first time as Visiting Fellow in the Laboratory of Genetics at the National Institute on Aging, NIH. After having spent almost three years investigating the cell death mechanisms associated with oocyte loss in a murine ovarian model, she was awarded the prestigious 4-year Welcome Trust PhD studentship in the United Kingdom. Laura received her doctoral degree in Cellular and Molecular Biology from the University of Dundee in October 2018, with dissertation work in Professor Sonia Rocha’s laboratory focused on the functional crosstalk between hypoxia and inflammation in cancer cell lines and Drosophila melanogaster. At LIBD, Dr. D’Ignazio is further developing her expertise in stem cell biology and neuroscience while continuing to pursue her interests in genetics and gene expression. She does this by using a multidisciplinary approach spanning human-induced pluripotent stem cell models (iPSC) and advanced genomics to study how mobile element misregulation contributes to the XDP pathology.