- Selected Publications
Feng Yang, M.D., Ph.D. is an Investigator at the Lieber Institute for Brain Development. His research interests focus primarily on cellular and molecular mechanisms underlying mental disorders, schizophrenia in particular, within circuits of prefrontal cortex, ventral tegmental area, basal forebrain and hippocampus. Dr. Yang received his medical degree in pediatrics from Chongqing Medical University, China. He received his Ph.D. in neurobiology from Shanghai Brain Research Institute (currently Institute of Neuroscience) at the Chinese Academy of Sciences in China. From 1998 to 2009, he joined Dr. Bai Lu’s laboratory as a postdoctoral fellow and staff scientist at the NICHD at NIH. Before moving to the Lieber Institute, he worked with Dr. Daniel Weinberger and Dr. Chris McBain as a staff scientist at both the NIMH and NICHD at the NIH.
Je HS, Yang F, Ji YY, Nagappan G, Hempstead B, Lu B. Role of Pro-Brain-Derived Neurotrophic Factor (proBDNF) to Mature BDNF Conversion in Activity-Dependent Competition at Developing Neuromuscular Synapses. PNAS 2012; Sep 25; 109 (39):15924-9. Epub 2012 Sep 10.
Papaleo F, Yang F, Garcia S, Chen JS, Lu B, Crawley JN, Weinberger DR. Dysbindin-1 Modulates Prefrontal Cortical Activity and Schizophrenia-like Behaviors via Dopamine/D2 Pathways. Molecular Psychiatry 2012; 17(1):85-98.
Huffaker SJ, Chen JS, Nicodemus KK, Sambataro F, Yang F, Mattay V, Lipska BK, Hyde TM, Song J, Rujescu D, Giegling I, Mayilyan K, Soghoyan A, Caforio G, Bertolino A, Meyer-Lindenberg A, Chang J, Ji YY, Egan M, Goldberg TE, Kleinman JE, Lu B, Weinberger DR. A novel, Primate-Specific Brain Isoform of KCNH2: Role in Hippocampal Biology, Neuronal Repolarization, Cognition, and Association with Schizophrenia. Nature Medicine 2009; 15: 509-518.
Yang F, Je HS, Ji YY, Nagappan G, Hempstead B, Lu B. ProBDNF-induced Synaptic Depression and Retraction at Developing Neuromuscular Synapses. J. Cell Biol. 2009; 185: 727-741.
Ji YY, Yang F, Papaleo F, Wang HX, Gao WJ, Weinberger DR, Lu B. Role of Dysbindin in Dopamine Receptor Trafficking, Cortical GABA Function and Working Memory. PNAS 2009; 106(46):19593-8.