Rahul Bharadwaj, Ph.D. is a postdoctoral research fellow with a focus on molecular gene expression regulation. His graduate thesis was focused on understanding how epigenetic driven chromatin architecture in postmortem human brain nuclei impacts gene expression. He has the distinction of pioneering the technique of ‘Chromosome Conformation Capture – 3C’ in postmortem human brain tissue with publications appearing in Neuron [84(5):997-1008] and The Journal of Neuroscience 33(29):11839-51, amongst others. The Schizophrenia Research Forum covered his novel findings in postmortem human brain chromatin architecture at the GAD1 genetic locus in a news article (http://www.schizophreniaforum.org/new/detail.asp?id=1936). He gained postdoctoral training for a year at the Johns Hopkins School of Medicine in the subjects of neuropathology and neuroanatomy. Aside from his research work, he also manages postmortem brain freezing and pathological assessment of consented Lieber brains as part of his role with the Neuropathology team at the Lieber Institute. His current projects include working on identifying genetic targets of clinical relevance in Alzheimer’s Disease, post-traumatic stress disorder and schizophrenia under supervision of Drs. Joel Kleinman, Thomas Hyde and Anand Mattay. He is specifically interested in how genetic variants use epigenetic mechanisms at the chromatin interface (chromatin looping, histone modifications) to alter expression of target genes.
LIBD Speaker Series: Bryan W. Luikart, Ph.D.
Understanding the Neurobiological Basis of Autism Using PTEN as a Genetic Model Bryan W. Luikart, Ph.D. Assistant Professor Department of Molecular and Systems Biology Geisel School of Medicine at Dartmouth When: September 26 2:00pm-3:00pm Where: The Lieber Institute for Brain […]